Can clinical algorithms deliver an accurate diagnosis of HIV infection in infancy?
نویسندگان
چکیده
Bulletin of the World Health Organization | July 2005, 83 (7) are continuously updating this analysis based on a rapidly growing body of data from more than 40 ongoing projects in 14 countries. A policy framework and tools to help implementation have been developed based on field experiences and operational research. Information about WHO’s work on private sector involvement in TB control can be found on the web site: http://www.who. int/tb/dots/ppm. Mahendradhata & Utarini highlight the fact that public–private collaboration for improved TB control takes place in a context of constrained resources and competing interests. Our analysis suggests that government investment is indeed crucial in order to ensure technical capacity-building in the private sector, managerial capacity-building in the public sector, improved supervision and quality control of private providers, and improved surveillance. Public funding is also needed in order to secure a supply of drugs and consumables free of charge to TB patients attending private clinics. While additional investments will be required, cost-effectiveness analysis of two collaborative projects in India has demonstrated that the amounts of such investments would be comparable, on a cost per successfully treated case basis, to those required by the public sector (3). From a societal perspective, a significant added value would be a substantial reduction in the financial burden on patients and, potentially, early detection and reduction in transmission of TB. From documented experiences, what do we already know about why partnerships work? As expected, the determinants of success are precisely the factors that help to counter some of the well-known barriers to collaboration (4). First, a genuine commitment on the part of the public sector demonstrating that it is indeed interested in working with private providers; second, justifiable additional investments — human and financial — to help build the collaboration and contribute further to TB control; third, a proper situational analysis to develop a locally appropriate task-mix for public and private providers; fourth, orientation and training of both public and private providers to prepare them to work together; and finally, a built-in monitoring and evaluation system to continue to measure the benefits and to improve upon the collaboration (2, 5). For Mahendradhata & Utarini’s own project, if they intend to apply first what they mentioned first — the strategy of strengthening regulatory structures — then a word of caution is called for. Regulation of private providers is indeed crucial and must be dealt with. To begin with a heavy emphasis on “regulating” providers, however, could turn the project into a non-starter. Experience shows that in public–private partnership building, when to employ a strategy is as important as the strategy itself. This and similar potential stumbling blocks could be avoided if private providers are involved in the process right from the first step of planning an intervention and, more importantly, in a spirit of partnership. O
منابع مشابه
The Diagnosis of HIV Infection in Infants and Children
It is estimated that the number of HIV infected children globally has increased from 1.6 million in 2001 to 3.3 million in 2012. The number of children below 15 years of age living with HIV has increased worldwide. Published data from recent studies confirmed dramatic survival benefit for infants started anti-retroviral therapy (ART) as early as possible after diagnosis of HI. Early confirmatio...
متن کاملAssessment of HCV Infection in Suspected Orphans Newborns by Real-Time PCR and HCV-Core Ag-Elisa
Background & Objective: HCV infection may be transmitted from an infected mother to her fetus in a low percentage however, it is the most important route of infancy HCV infection. The chance of HCV transmission in HIV/HCV co-infected mothers is higher than that in HCV mono-infected ones. The aim of this study is to assess HCV infection status in orphan newborns in Shiraz, Iran by quantitative P...
متن کاملIntestinal Pseudo-Obstruction as an Unusual Gastrointestinal Presentation in Pediatric Human Immunodeficiency Virus Infection
Intestinal pseudo-obstruction is a condition in which the intestine’s ability to push food through is reduced. It often leads to the dilation of the various parts of the bowel. It can be idiopathic or inherited from a parent, or caused by another disease. We report a rare case of human immunodeficiency virus (HIV) infection in a 3-year-old boy who referred with acute abdominal pain, and was lat...
متن کامل-MicroRNAs: New biomarkers for diagnosing HIV-
According to the increasing number of AIDS patients and their deaths, Treatment is a very important debate to prevent this Which is dependent on early and Accurate diagnosis. Currently, there are different diagnostic methods, including virus cultures, rapid tests, western blot, and other tests for this infection. Among these, HIV RNA TESTING, especially APTIMA HIV RNA ASSAY and fourth generatio...
متن کاملFungal infections of the CNS - Section 1
While fungal infections of the CNS are relatively rare, they have become more common with the increasing number of individuals who are immunocompromised due to HIV/AIDS, immunosuppressive therapies, invasive diagnosis and treatment methods, and organ transplants. CNS fungal infections present many diagnostic and therapeutic challenges and are associated with a high mortality rate. Cryptococcal ...
متن کاملOccult Hepatitis B Demonstrated by Anti-HBc and HBV DNA in HIV-Positive Patients
Background: In patients who are hepatitis B virus (HBV) DNA-positive, but HBV surface antigen (HBsAg) -negative, the infection is referred to as occult hepatitis B infection (OBI). Occult HBV infection is harmful when other liver diseases are present, and can aggravate liver damage in in patients with chronic liver diseases. In human immunodeficiency virus (HIV) infection the suppression of vir...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Bulletin of the World Health Organization
دوره 83 7 شماره
صفحات -
تاریخ انتشار 2005